| Day 1 | Arrival in Rome Arrival at one of Rome´s airports. Go to the hotel. Go for a walk and have dinner in the centre. Night in Rome. | |
| Day 2 | Vatican City and historic centre Visit the Vatican City: Sistine Chapel and St. Peter´s Basilica. Visit the historic centre of Rome, going by the Piazza Navona, the Pantheon, the Trevi Fountain, the Piazza di Spagna and the Piazza del Poppolo. Night in Rome. | |
| Day 3 | Ancient Rome and Trastevere Visit the ruins of ancient Rome: the Colisseum, the Forum and the Roman Circus. Walk around and have dinner in Trastevere. Night in Rome. | |
| Day 4 | South of Tuscany Visit by hire car the towns in the south of Tuscany (Montepulciano, Pienza and Montalcino). Night in Siena. | |
| Day 5 | Siena and the north of Tuscany Visit to the Duomo and the Piazza del Campo di Siena. Visit by hire car the towns in the north of Tuscany (Monteriggioni, San Gimignano). Night close to San Gimignano. | |
| Day 6 | Chianti and Florence Visit by hire car to the Chianti region. Arrive in Florence and walk around the historic centre. Night in Florence. | |
| Day 7 | Florence, Pisa and Luca Visit to the Galleria Degli Uffizi, the world´s most important collection of Renaissance art (Michelangelo, Botticelli, Leonardo da Vinci, Raphael...). Go by car to the towns of Luca and Pisa (leaning tower). Return to Florence and spend the night in the city. | |
| Day 8 | Venice Go to Venice by train (or hire car if you prefer). Visit the Piazza San Marcos.Night in Venice. | |
| Day 9 | Venice Walk through the most emblematic parts of Venice: San Polo, Dorsoduro and Santa Croce. Night in Venice. | |
| Day 10 | Venice and Verona Visit to Murano Island and walk through the Cannaregio district. Go by train to Verona (or by hire car if you prefer). Visit the historic centre of Verona. Opera at the Verona Arena (opera season). Night in Verona. | |
| Day 11 | Lake Como and Milan Go by hire car to Lake Como visiting Belaggio and Como. Arrive in Milan. Walk and dinner around the areas of Brera, Navigli and Ticinese. Night in Milan. | |
| Day 12 | Milan and Portofino Visit the historic centre of Milan. Go by train to Santa Margherita Ligure. Spend the afternoon in Portofino. Night in Santa Margherita Ligure. | |
| Day 13 | Cinqueterre Go on an excursion around the Cinqueterre nature park combing train, walking and ferry. Night in Santa Margherita Ligure. | |
| Day 14 | Camogli and San Fruttuoso Visit the fishing village of Camogli. Go on an excursion to San Fruttuoso. Go there and back by train. Night in city of departure (Milan or Rome, depending on your flight back to home). | |
| Day 15 | Back home Flight back home. Map of the route:  See map of the route on Google Maps | |
| |